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NAD+ declines with age, affecting health & performance. Find the best solution for you today.
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NAD+ Declines With Age
NAD+ levels naturally decline with age, impacting energy, metabolism, and cellular repair.
NAD+ is a vital coenzyme found in every cell of your body responsible for converting food into energy to fuel your metabolism and daily performance.
It repairs damaged DNA to keep your cells functioning optimally. It supports brain and muscle function for better focus, endurance, and recovery.
But every day that passes, our NAD+ naturally decline, dropping almost 50% by middle age.
Boosting Your NAD+ Levels
To restore NAD+ levels, your body need precursors – compounds that convert to NAD+ inside your cells.
Scientific studies have highlighted two NAD+ precursors as being the most effective: NR and NMN.
NMN is a more direct NAD+ precursors that is currently in-review with the UK Food Safety Association (FSA).
NR is highly bioavailable making it easily absorbed and quickly converted into NAD+. NR has been authorised by the FSA and the European Food Safety Authority (EFSA).
But Not All Supplements Are Created Equally.
We take our supplements. Our family takes our supplements. Our friends take our supplements.
For that reason safety is our highest priority.
Many brands cut corners bulking their product with low-purity ingredients and fillers.
We guarantee our quality through third-party SGS testing for purity and contaminents. We stand behind our product and provide testing certificates.
Purity - The Foundation Of An Effective Supplement.
Your body deserves the best fuel- not cheap fillers or low-grade compounds.
✔ High purity, bioavailable ingredients.
✔ No unnecessary additives.
✔ Tested for potency.
Inferior ingredients mean ineffective results.
Your Safety Comes First
Every batch undergoes independent third-party testing to guarantee purity, potency, and safety. We test for:
✔ Heavy metals & toxins
✔ Ingredient verification
✔ Stability & shelf-life
Many brands skip third-party testing, leaving questionable quality and safety. We prove our purity, and share the results with you.
No Hype, Just Proven Results
We rely on peer-reviewed, human clinical trials. Our supplements are formulated based on real research, ensuring they:
✔ Follow authorised dosages
✔ Based on human studies
✔ Continual development
Many brands overdose – charging your more for the same results, or underdose packing supplements with cheap fillers.
NADBio Premium NAD+ Supplements
Premium Ingredients
Purity over profits, our supplements are created using premium ingredients.
Third-Party Testing
SGS third-party testing for every batch verifying purity and contaminants
Advanced Delivery
High-stability capsule and powder form for optimal bioavailability.
Based In The UK
We're located and ship from the UK adhering to strict UK quality standards.
The NADBio Difference
We take these supplements ourselves. We supply our friends and family, and we wouldn’t settle for anything less than the best quality.
✅ Premium purity.
✅ Verified by independent labs.
✅ Proven by science.
Your health matters – choose a supplement you can trust.
Join the NAD+ revolution.
Supporting Thousands on Their Health journey. Backed by Science, Trusted by You.
(Rated 4.8 / 5 by our customers)
- Ultra-Pure NAD+ Supplements - Third-Party Certified
- Millions Of Tablets Sold Worldwide
- The Trusted Supplements Of High Performers
What to expect From
NAD+ Supplements?
Taking NAD+ supplements may support key biological processes that naturally decline with age. Optimised NAD+ levels can contribute, help, support, and are associated with:
Healthy Ageing
Metabolic Function
Energy Production
Liver & Cardiovascular Function
Cognitive Performance
Endurance & Recovery
Circadian Rhythm
Immune Function
The Science Behind NAD+ A Deeper Dive
A fundamental coenzyme responsible for cellular energy, DNA repair, and metabolic function. But how exactly does it work? And why do scientists believe that maintaining NAD+ levels can support healthier aging, cognitive function, and overall vitality?
How NAD+ Powers Your Cells
NAD+ is an essential pyridine nucleotide involved in redox metabolism, enzymatic activity, and cellular homeostasis.
As a coenzyme, it facilitates hydride ion transfer reactions critical for oxidative phosphorylation and ATP production.
Beyond its role in metabolism, NAD+ is a substrate for ADP-ribosylation, sirtuin activation, and DNA repair enzymes, directly influencing cell survival, genomic stability, and mitochondrial function.
However, NAD+ levels decline with age, attributed to increased CD38 and PARP1 activity, leading to higher NAD+ consumption and an overall depletion in cellular pools.
This depletion compromises mitochondrial efficiency, metabolic integrity, and proteostasis, which are hallmarks of aging-related decline.
Effective NAD+ PRecursors - The Tricky Part
NAD+ functions as a hydrogen carrier within the electron transport chain, accepting electrons from NADH and facilitating their transfer to Complex I (NADH dehydrogenase).
This process establishes a proton gradient across the inner mitochondrial membrane, driving ATP synthase-mediated oxidative phosphorylation.
The efficiency of ATP synthesis is directly proportional to intracellular NAD+ availability, linking NAD+ depletion to mitochondrial dysfunction and bioenergetic failure.
In addition to ATP generation, NAD+ is an obligatory cofactor for key metabolic pathways including glycolysis, β-oxidation, and the tricarboxylic acid cycle.
It modulates NADH/NAD+ redox balance, ensuring metabolic flexibility in response to energy demand fluctuations. Reduced NAD+ levels impair lipid metabolism, glucose homeostasis, and insulin sensitivity, predisposing individuals to metabolic disorders and age-associated dysfunction.
Founded In Science
NAD+ Levels & Aging
A study published in Cell Metabolism (Zhang et al., 2016) found that NAD+ declines by up to 50% in middle-aged adults. Restoring NAD+ levels enhanced mitochondrial function and reduced metabolic decline in aging models.
NR & NMN Clinical Trials
A randomised, placebo-controlled human trial (Nature Communications, 2022) showed that NR supplementation significantly increased blood NAD+ levels, improving muscle function and energy metabolism.
A 2021 study in Science Advances tested NMN supplementation in humans and reported increased endurance, improved insulin sensitivity, and enhanced NAD+ levels.
Sirtuins, DNA Repair & Longevity
Research in Nature (Imai & Guarente, 2014) demonstrated that boosting NAD+ activates sirtuins, which extend lifespan in animal models and improve cellular health.
A study in Nature Communications (Yoshino et al., 2018) found that increasing NAD+ through NR supplementation improved age-related mitochondrial dysfunction in humans.
These findings solidify NR and NMN as powerful interventions for NAD+ restoration and cellular support.
Why NAD+ Supplements Are Generating So Much Excitement
We’re not just living longer than ever, we’re living healthier for longer.
NAD+ supplements are changing how we think about energy, aging, and longevity.
As science uncovers the link between declining NAD+ levels and age-related slowdown, researchers have found that boosting NAD+ can help support metabolism, brain function, and cellular repair.
Leading experts in longevity now see NAD+ as a key player in maintaining health as we age, with growing clinical studies showing real benefits.
With advanced NR and NMN supplements now available, people can actively support their cells and feel their best for longer – making NAD+ one of the most exciting breakthroughs in wellness today.
NAD+ Supplements.
Certified Pure. For The UK.
We’re proud of our NAD supplement’s purity. We ensuring strict quality control, certified lab environments, and full compliance with UK regulations. We prioritise purity, safety, and transparency – so you know exactly what you’re getting.
UK Certification
Unlike many alternatives, our NAD supplements exceed UK safety standards. Good Manufacturing Practices and rigorous third-party testing guarantee a premium product.
Outstanding support
We’re a UK company, paying UK taxes and offering fast, with UK customer support. Expect reliable delivery and assistance from a team that values your trust.
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References
Enhanced Energy Production
NAD⁺ is a critical cofactor in normal cellular energy processes, helping to enable glycolysis, the TCA cycle, and oxidative phosphorylation. By supporting these pathways, NAD⁺ may help maintain healthy ATP levels for improved cellular energy balance.Mitochondrial Support
Maintaining higher NAD⁺ levels is associated with better NAD⁺/NADH balance, which may help support mitochondrial function and reduce excessive production of reactive oxygen species (ROS), contributing to overall cell vitality.DNA Repair Mechanisms
NAD⁺ is a necessary substrate for enzymes like PARPs, which help repair normal DNA damage. By supporting the cell’s DNA repair capabilities, it can promote genomic stability and reduce the risk of errors accumulating over time.Neuroprotection and Brain Health
In the nervous system, NAD⁺ contributes to healthy neuronal metabolism and cellular resilience. Emerging research suggests higher NAD⁺ levels may help maintain normal cognitive function and brain health as part of healthy aging.Stem Cell Activity and Tissue Maintenance
Adequate NAD⁺ levels are linked to supporting normal stem cell function, which is essential for routine tissue upkeep. By helping maintain a healthy NAD⁺/NADH ratio, it may promote more efficient repair processes in the body.Immune System Support
NAD⁺ influences immune cell metabolism and function. Maintaining balanced NAD⁺ levels may support the body’s natural defenses and help immune cells respond effectively to challenges, though more research is ongoing.Oxidative Stress Balance
By facilitating efficient metabolic reactions and supporting antioxidant pathways, NAD⁺ may help the body balance ROS production and elimination. This could contribute to the protection of cellular components from oxidative stress.Healthy Aging and Cellular Maintenance
NAD⁺ is associated with sirtuin activity—proteins involved in cellular stress responses and regulation of normal aging processes. Supporting NAD⁺ levels may help maintain overall cellular health, though individual results can vary. Disclaimer
General Information
The information provided on this website, including but not limited to text, images, and product descriptions, is for informational purposes only and should not be considered medical advice. Our NMN supplements are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional before taking any dietary supplements, especially if you are pregnant, nursing, taking medication, or have a medical condition.
Regulatory Compliance
Our NMN supplements are produced in the UK and adhere to strict Good Manufacturing Practices (GMP) for quality and safety. However, NMN is classified as a dietary supplement, not a medicine, and therefore is not regulated as a pharmaceutical product. Any claims regarding NMN’s benefits are based on emerging scientific research, and individual results may vary.
Scientific & Research Information
This website may reference scientific studies, research findings, or third-party publications related to NMN, NAD⁺, and cellular health. While we strive to provide accurate and up-to-date information, research is ongoing, and conclusions may change as new studies emerge. The information presented does not constitute medical or professional advice and should not be relied upon for making health-related decisions.
Use of Products
The recommended dosage and usage guidelines for our NMN supplements are based on existing research and general industry recommendations. Individual responses to NMN may vary, and results are not guaranteed. If you experience any adverse effects, discontinue use immediately and seek medical advice.
No Liability
We do not accept liability for any injury, loss, or damage resulting from the use of this website or the purchase and consumption of our products. By using our website and purchasing our NMN supplements, you acknowledge and agree that you do so at your own risk.
External Links & Third-Party Information
This website may contain links to third-party sources, studies, or articles for informational purposes. We do not endorse or assume responsibility for the content, accuracy, or claims made by external websites.
Changes to This Disclaimer
We reserve the right to modify, update, or remove any part of this disclaimer at any time without prior notice. It is your responsibility to review this page periodically for any changes.
Contact Information
If you have any questions regarding this disclaimer or our products, please contact our customer support team at [email protected].
